GLP-1 Nausea Relief: 8 Remedies That Actually Work (2026 Guide)

Nausea is the most commonly reported side effect of GLP-1 medications. In clinical trials, 40-44% of participants experienced it. If you are reading this while your stomach is doing things you did not consent to, you are in good company.

Why GLP-1s Cause Nausea

GLP-1 receptor agonists slow gastric emptying — your stomach empties more slowly than usual. This is actually part of how the medication reduces appetite, but it can leave food sitting longer than your digestive system expects, triggering nausea signals.

Remedies That Actually Help

• Ginger. Real ginger tea, ginger chews, or ginger capsules. A 2020 meta-analysis in Nutrients confirmed ginger reduces nausea intensity across multiple conditions.
• Smaller, more frequent meals. Three large meals become five smaller ones. Less volume in the stomach at any given time means less nausea.
• Avoid lying down after eating. Wait at least 30 minutes. Gravity helps.
• Peppermint. Peppermint tea or inhaling peppermint oil can settle nausea quickly.
• Cold foods over hot. Strong food smells can trigger nausea. Cold meals like salads, yogurt, and sandwiches produce fewer aromatic triggers.
• Stay hydrated. Dehydration makes nausea worse. Sip water throughout the day rather than gulping.
• Injection timing. Many people find that injecting in the evening means peak nausea occurs during sleep.

When It Is More Than Discomfort

Contact your healthcare provider if nausea is severe enough that you cannot keep fluids down for more than 24 hours, if you notice signs of dehydration, or if it persists beyond 8-12 weeks without improvement.

This Part Gets Better

For the vast majority of people, nausea is worst in the first 4-6 weeks and then gradually resolves. Each week that passes is your body learning to work with the medication rather than against it. You are building resilience, and that matters.